Striatal degeneration induced by mitochondrial blockade is prevented by biologically delivered NGF.

Frim, D M; Simpson, J; Uhler, T A; Short, M P; Bossi, S R; Breakefield, X O; Isacson, O

Frim, D M; Simpson, J; Uhler, T A; Short, M P; Bossi, S R; Breakefield, X O; Isacson, O.

Affiliation

Frim DM; Neuroregeneration Laboratory, McLean Hospital, Belmont, Massachusetts 02178.

J Neurosci Res ; 35(4): 452-8, 1993 Jul 01.

Article in En | MEDLINE | ID: mdl-8103116

Subject(s)

Corpus Striatum/drug effects; Mitochondria/drug effects; Nerve Degeneration/drug effects; Nerve Growth Factors/pharmacology; Acetylcholinesterase/metabolism; Animals; Brain Tissue Transplantation/physiology; Cell Line; Corpus Striatum/anatomy & histology; Corpus Striatum/ultrastructure; Energy Metabolism/physiology; Fibroblasts/metabolism; Genetic Engineering; Immunohistochemistry; Male; Nerve Growth Factors/genetics; Nerve Growth Factors/metabolism; Neurotoxins/pharmacology; Nitro Compounds; Propionates/pharmacology; Rats; Rats, Sprague-Dawley; Tyrosine 3-Monooxygenase/metabolism

Search on Google

Add to My VHL

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Corpus Striatum / Mitochondria / Nerve Degeneration / Nerve Growth Factors Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Neurosci Res Year: 1993 Document type: Article Country of publication: United States

Search on Google

Add to My VHL

XML

PubMed Links