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Precise localization on chromosome 12 of the ATF-1 gene by fluorescence in situ hybridization.
Desmaze, C; Zucman, J; Delattre, O; Melot, T; Thomas, G; Aurias, A.
Affiliation
  • Desmaze C; Laboratoire de Génétique des Tumeurs, INSERM CJF 9201, Institut Curie, Paris, France.
Hum Genet ; 93(2): 207-8, 1994 Feb.
Article in En | MEDLINE | ID: mdl-8112749
The ATF-1 gene encodes for a transcription factor normally regulated by cAMP (Hai et al. 1989, Yoshimura et al. 1990). Recently, it has been shown to be involved in the recurrent t(12;22) translocation observed in soft tissue malignant melanoma, in a fusion gene with the EWS gene (Zucman et al. 1993). We report here on its precise localization on chromosome 12 by fluorescence in situ hybridization.
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Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Chromosomes, Human, Pair 12 / In Situ Hybridization, Fluorescence / DNA-Binding Proteins Limits: Humans Language: En Journal: Hum Genet Year: 1994 Document type: Article Affiliation country: France Country of publication: Germany
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Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Chromosomes, Human, Pair 12 / In Situ Hybridization, Fluorescence / DNA-Binding Proteins Limits: Humans Language: En Journal: Hum Genet Year: 1994 Document type: Article Affiliation country: France Country of publication: Germany