A new consistent model explaining structure (conformation)-activity relationships of opiates with mu-selectivity.

Brandt, W; Barth, A; Höltje, H D

Brandt, W; Barth, A; Höltje, H D.

Affiliation

Brandt W; Department of Biochemistry/Biotechnology, Martin-Luther-University, Halle, Germany.

Drug Des Discov ; 10(4): 257-83, 1993.

Article in En | MEDLINE | ID: mdl-8148469

Subject(s)

Narcotics/pharmacology; Receptors, Opioid, mu/drug effects; Analgesics/pharmacology; Crystallography, X-Ray; Fentanyl/analogs & derivatives; Fentanyl/pharmacology; Models, Molecular; Molecular Conformation; Narcotics/chemistry; Phenazocine/chemistry; Phenazocine/pharmacology; Stereoisomerism; Structure-Activity Relationship; Tomography, Emission-Computed

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Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Opioid, mu / Narcotics Type of study: Prognostic_studies Language: En Journal: Drug Des Discov Journal subject: FARMACOLOGIA Year: 1993 Document type: Article Affiliation country: Germany Country of publication: Switzerland

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