High level production of human growth hormone in the milk of transgenic mice: the upstream region of the rabbit whey acidic protein (WAP) gene targets transgene expression to the mammary gland.

Devinoy, E; Thépot, D; Stinnakre, M G; Fontaine, M L; Grabowski, H; Puissant, C; Pavirani, A; Houdebine, L M

Devinoy, E; Thépot, D; Stinnakre, M G; Fontaine, M L; Grabowski, H; Puissant, C; Pavirani, A; Houdebine, L M.

Affiliation

Devinoy E; Laboratoire de Biologie Cellulaire et Moléculaire, Institut National de la Recherche Agronomique, Jouy en Josas, France.

Transgenic Res ; 3(2): 79-89, 1994 Mar.

Article in En | MEDLINE | ID: mdl-8193641

Subject(s)

Growth Hormone/biosynthesis; Lactation/metabolism; Mammary Glands, Animal/metabolism; Milk Proteins/genetics; Recombinant Fusion Proteins/genetics; Animals; Estrus/metabolism; Female; Gene Expression Regulation/genetics; Growth Hormone/blood; Growth Hormone/genetics; Humans; Male; Mammary Glands, Animal/growth & development; Mice; Mice, Inbred C57BL; Mice, Transgenic; Milk/chemistry; Milk Proteins/biosynthesis; Pregnancy; RNA, Messenger/analysis; Rabbits; Recombinant Fusion Proteins/biosynthesis; Regulatory Sequences, Nucleic Acid/genetics; Tissue Distribution

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Collection: 01-internacional Database: MEDLINE Main subject: Recombinant Fusion Proteins / Lactation / Growth Hormone / Mammary Glands, Animal / Milk Proteins Limits: Animals / Female / Humans / Male / Pregnancy Language: En Journal: Transgenic Res Journal subject: BIOLOGIA MOLECULAR Year: 1994 Document type: Article Affiliation country: France Country of publication: Netherlands

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