Aromatic and amine substituent effects on the apparent lipophilicities of N-[(2-pyrrolidinyl)methyl]-substituted benzamides.

Schmidt, D E; Votaw, J R; Kessler, R M; de Paulis, T

Schmidt, D E; Votaw, J R; Kessler, R M; de Paulis, T.

Affiliation

Schmidt DE; Department of Psychiatry, Vanderbilt University, Nashville, TN 37235.

J Pharm Sci ; 83(3): 305-15, 1994 Mar.

Article in En | MEDLINE | ID: mdl-8207673

Subject(s)

Benzamides/chemistry; Dopamine D2 Receptor Antagonists; Pyrrolidines/chemistry; Amines/chemistry; Benzamides/chemical synthesis; Chemical Phenomena; Chemistry, Physical; Chromatography, High Pressure Liquid; Fluorine/chemistry; Iodine/chemistry; Lipids/chemistry; Magnetic Resonance Spectroscopy; Molecular Conformation; Pyrrolidines/chemical synthesis; Regression Analysis; Solubility; Structure-Activity Relationship; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon

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Collection: 01-internacional Database: MEDLINE Main subject: Pyrrolidines / Benzamides / Dopamine D2 Receptor Antagonists Type of study: Diagnostic_studies Language: En Journal: J Pharm Sci Year: 1994 Document type: Article Country of publication: United States

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