Medullary carcinoma of the breast. A multicenter study of its diagnostic consistency.
Arch Pathol Lab Med
; 117(10): 1005-8, 1993 Oct.
Article
in En
| MEDLINE
| ID: mdl-8215820
ABSTRACT
Nine pathologists from different institutions reviewed in a double-blind study 16 breast tumors previously indexed as typical medullary carcinoma, atypical medullary carcinoma, or infiltrative ductal carcinoma. A set of 16 slides was circulated two times among the nine pathologists. The diagnoses of typical and atypical medullary carcinomas were based on a definition given by Ridolfi et al. The interobserver and intraobserver agreement was low, with a kappa value of less than .50. The only histological criterion that had more than 50% agreement was the presence or absence of an in situ component in the tumor, assuming that the disagreement of one pathologist is accepted. This study is a snapshot of the problems encountered in the diagnosis of typical medullary carcinoma in a routine context and it shows high levels of variations in diagnostic consistency.
Search on Google
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Breast Neoplasms
/
Carcinoma, Medullary
Type of study:
Clinical_trials
/
Diagnostic_studies
Limits:
Female
/
Humans
Language:
En
Journal:
Arch Pathol Lab Med
Year:
1993
Document type:
Article
Affiliation country:
France