Interaction of DNA polymerase and DNA helicase within the bacteriophage T4 DNA replication complex. Leading strand synthesis by the T4 DNA polymerase mutant A737V (tsL141) requires the T4 gene 59 helicase assembly protein.

Spacciapoli, P; Nossal, N G

Spacciapoli, P; Nossal, N G.

Affiliation

Spacciapoli P; Laboratory of Biochemical Pharmacology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892.

J Biol Chem ; 269(1): 447-55, 1994 Jan 07.

Article in En | MEDLINE | ID: mdl-8276834

Subject(s)

Bacteriophage T4/enzymology; DNA Helicases/metabolism; DNA, Viral/biosynthesis; DNA-Directed DNA Polymerase/metabolism; Viral Proteins/metabolism; Bacteriophage T4/genetics; DNA, Viral/metabolism; DNA-Directed DNA Polymerase/genetics; Mutation

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Collection: 01-internacional Database: MEDLINE Main subject: Viral Proteins / DNA, Viral / Bacteriophage T4 / DNA Helicases / DNA-Directed DNA Polymerase Language: En Journal: J Biol Chem Year: 1994 Document type: Article Country of publication: United States

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