Purification and characterization of a novel tetradecapeptide that modulates oesophagus motility in Lymnaea stagnalis.
Biochem Biophys Res Commun
; 197(3): 1056-61, 1993 Dec 30.
Article
in En
| MEDLINE
| ID: mdl-8280120
ABSTRACT
The isolated oesophagus of Lymnaea stagnalis was used as a bioassay preparation to identify peptides that modulate the activity of the oesophagus. Several modulatory messengers were detected from the oesophageal extract. One of these, having an excitatory action, was further purified from both the oesophagus and the central nervous system through high performance gel permeation chromatography followed by serial reversed phase high performance liquid chromatography. The purified peptide was chemically characterized through amino acid sequencing and mass spectrometry as GFRANSASRVAHGY-NH2.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Neuropeptides
/
Esophagus
/
Lymnaea
/
Nervous System Physiological Phenomena
Limits:
Animals
Language:
En
Journal:
Biochem Biophys Res Commun
Year:
1993
Document type:
Article
Affiliation country:
Netherlands