Proteinase 3: substrate specificity and possible pathogenetic effect of Wegener's granulomatosis autoantibodies (c-ANCA) by dysregulation of the enzyme.

Dolman, K M; van de Wiel, B A; Kam, C M; Kerrigan, J E; Hack, C E; von dem Borne, A E; Powers, J C; Goldschmeding, R

Dolman, K M; van de Wiel, B A; Kam, C M; Kerrigan, J E; Hack, C E; von dem Borne, A E; Powers, J C; Goldschmeding, R.

Affiliation

Dolman KM; Central Laboratory of The Netherlands, Red Cross Blood Transfusion Service, Amsterdam.

Adv Exp Med Biol ; 336: 55-60, 1993.

Article in En | MEDLINE | ID: mdl-8296674

Subject(s)

Autoantibodies/pharmacology; Granulomatosis with Polyangiitis/immunology; Immunoglobulin G/pharmacology; Serine Endopeptidases/metabolism; Amino Acid Sequence; Antibodies, Antineutrophil Cytoplasmic; Elastin/metabolism; Humans; Molecular Sequence Data; Myeloblastin; Peptides/chemistry; Peptides/metabolism; Serine Endopeptidases/immunology; Substrate Specificity; alpha 1-Antitrypsin/pharmacology

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Collection: 01-internacional Database: MEDLINE Main subject: Autoantibodies / Immunoglobulin G / Serine Endopeptidases / Granulomatosis with Polyangiitis Limits: Humans Language: En Journal: Adv Exp Med Biol Year: 1993 Document type: Article Country of publication: United States

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