[Anti-centriole antibodies and high neuron-specific enolase activity in a patient with Raynaud phenomenon, cerebrovascular lesions, and ischemic finger necrosis--a functional relationship?]. / Anti-Zentriolen-Antikörper und hohe neuronenspezifische Enolase-Aktivität bei einer Patientin mit Raynaud-Phänomen, zerebrovaskulären Läsionen und ischämischen Fingernekrosen--ein assoziierter Befund?
Immun Infekt
; 21 Suppl 1: 22-3, 1993 Apr.
Article
in De
| MEDLINE
| ID: mdl-8344679
ABSTRACT
In a 49-year-old patient with acute thrombangitis obliterans, several vascular risk factors and associated features of collagen vascular disease, we observed anti-centriole autoantibodies and a strongly elevated neuron-specific enolase (NSE). The latter could not be attributed to an underlying malignant or neuroendocrine disease. The recent identification of NSE as a centrosomal protein suggests a causal relationship between anti-centriole autoantibodies and elevated serum NSE levels.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Phosphopyruvate Hydratase
/
Raynaud Disease
/
Autoantibodies
/
Autoimmune Diseases
/
Centrioles
/
Cerebrovascular Disorders
Type of study:
Prognostic_studies
/
Risk_factors_studies
Limits:
Female
/
Humans
/
Middle aged
Language:
De
Journal:
Immun Infekt
Year:
1993
Document type:
Article