The effect of NMeTyr5 substitution in luteinizing hormone-releasing hormone antagonists.

Haviv, F; Fitzpatrick, T D; Nichols, C J; Swenson, R E; Mort, N A; Bush, E N; Diaz, G; Nguyen, A T; Holst, M R; Cybulski, V A

Haviv, F; Fitzpatrick, T D; Nichols, C J; Swenson, R E; Mort, N A; Bush, E N; Diaz, G; Nguyen, A T; Holst, M R; Cybulski, V A.

Affiliation

Haviv F; TAP Pharmaceuticals Inc., Abbott Laboratories, Abbott Park, Illinois 60064.

J Med Chem ; 36(7): 928-33, 1993 Apr 02.

Article in En | MEDLINE | ID: mdl-8385226

Subject(s)

Gonadotropin-Releasing Hormone/antagonists & inhibitors; Methyltyrosines/chemical synthesis; Peptides/chemical synthesis; Amino Acid Sequence; Animals; Methyltyrosines/metabolism; Methyltyrosines/pharmacology; Molecular Sequence Data; Peptides/metabolism; Peptides/pharmacology; Rats; Receptors, LHRH/metabolism; Structure-Activity Relationship

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Collection: 01-internacional Database: MEDLINE Main subject: Peptides / Gonadotropin-Releasing Hormone / Methyltyrosines Limits: Animals Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 1993 Document type: Article

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