Biochemical characteristics and cellular regulation of phosphodiesterase IV.

Torphy, T J; DeWolf, W E; Green, D W; Livi, G P

Torphy, T J; DeWolf, W E; Green, D W; Livi, G P.

Affiliation

Torphy TJ; Department of Pharmacology, SmithKline Beecham Pharmaceuticals, King of Prussia, Pennsylvania 19406.

Agents Actions Suppl ; 43: 51-71, 1993.

Article in En | MEDLINE | ID: mdl-8396319

Subject(s)

3',5'-Cyclic-AMP Phosphodiesterases; Phosphoric Diester Hydrolases/chemistry; Animals; Binding Sites/physiology; Cell Line; Cyclic Nucleotide Phosphodiesterases, Type 4; Humans; Kinetics; Phosphodiesterase Inhibitors/metabolism; Phosphoric Diester Hydrolases/isolation & purification; Phosphoric Diester Hydrolases/physiology; Pyrrolidinones/metabolism; Recombinant Proteins/antagonists & inhibitors; Recombinant Proteins/chemistry; Recombinant Proteins/isolation & purification; Rolipram; Up-Regulation/physiology

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Collection: 01-internacional Database: MEDLINE Main subject: 3',5'-Cyclic-AMP Phosphodiesterases / Phosphoric Diester Hydrolases Limits: Animals / Humans Language: En Journal: Agents Actions Suppl Year: 1993 Document type: Article Country of publication: Switzerland

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