The inhibition by fatty acids of receptor-mediated calcium movements in Jurkat T-cells is due to increased calcium extrusion.

Breittmayer, J P; Pelassy, C; Cousin, J L; Bernard, A; Aussel, C

Breittmayer, J P; Pelassy, C; Cousin, J L; Bernard, A; Aussel, C.

Affiliation

Breittmayer JP; Interactions Cellularies en Immunologie et Immunopathologie, Institut National de la Santé et de la Recherche Médicale U343, Nice, France.

J Biol Chem ; 268(28): 20812-7, 1993 Oct 05.

Article in En | MEDLINE | ID: mdl-8407910

Subject(s)

Antibodies, Monoclonal/physiology; CD3 Complex/metabolism; Calcium/metabolism; Fatty Acids/pharmacology; Signal Transduction/drug effects; T-Lymphocytes/drug effects; Calcium-Transporting ATPases/antagonists & inhibitors; Cell Line; Humans; Ionomycin/pharmacology; Lymphocyte Activation; Phosphatidylserines/biosynthesis; T-Lymphocytes/metabolism; Terpenes/pharmacology; Thapsigargin

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Collection: 01-internacional Database: MEDLINE Main subject: T-Lymphocytes / Signal Transduction / Calcium / CD3 Complex / Fatty Acids / Antibodies, Monoclonal Limits: Humans Language: En Journal: J Biol Chem Year: 1993 Document type: Article Affiliation country: France

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