Adaptor Proteins, Signal Transducing; Calmodulin-Binding Proteins/chemistry; Carrier Proteins/metabolism; DNA-Binding Proteins/metabolism; Heat-Shock Proteins/metabolism; Phosphoprotein Phosphatases/chemistry; Tacrolimus/metabolism; A Kinase Anchor Proteins; Amino Acid Sequence; Binding Sites; Calcineurin; Calcium/metabolism; Calmodulin-Binding Proteins/antagonists & inhibitors; Calmodulin-Binding Proteins/metabolism; Calmodulin-Binding Proteins/ultrastructure; Carrier Proteins/chemistry; Crystallization; Crystallography, X-Ray; DNA-Binding Proteins/chemistry; Enzyme Inhibitors/metabolism; Enzyme Inhibitors/pharmacology; Heat-Shock Proteins/chemistry; Humans; Hydrogen Bonding; Models, Molecular; Molecular Sequence Data; Phosphoprotein Phosphatases/antagonists & inhibitors; Phosphoprotein Phosphatases/metabolism; Phosphoprotein Phosphatases/ultrastructure; Protein Conformation; Protein Structure, Secondary; Proteins/metabolism; Proteins/pharmacology; Recombinant Proteins/chemistry; Tacrolimus/chemistry; Tacrolimus Binding Proteins; Water/metabolism