Effect of urinary alkalinisation and acidification on the tissue distribution of hexachlorophene in rats.

Flanagan, R J; Ruprah, M; Strutt, A V; Malarkey, P; Cockburn, A

Flanagan, R J; Ruprah, M; Strutt, A V; Malarkey, P; Cockburn, A.

Affiliation

Flanagan RJ; Poisons Unit, Guy's and St Thomas' Hospital Trust, London, UK.

Hum Exp Toxicol ; 14(10): 795-800, 1995 Oct.

Article in En | MEDLINE | ID: mdl-8562119

Subject(s)

Anti-Infective Agents, Local/pharmacokinetics; Hexachlorophene/pharmacokinetics; Urine/chemistry; Ammonium Chloride/pharmacology; Animals; Anti-Infective Agents, Local/blood; Anti-Infective Agents, Local/toxicity; Body Temperature/drug effects; Body Weight/drug effects; Hexachlorophene/blood; Hexachlorophene/toxicity; Hydrogen-Ion Concentration; Kidney/metabolism; Liver/metabolism; Male; Organ Size/drug effects; Rats; Rats, Sprague-Dawley; Sodium Bicarbonate/pharmacology; Tissue Distribution

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Collection: 01-internacional Database: MEDLINE Main subject: Urine / Hexachlorophene / Anti-Infective Agents, Local Limits: Animals Language: En Journal: Hum Exp Toxicol Journal subject: TOXICOLOGIA Year: 1995 Document type: Article Affiliation country: United kingdom Country of publication: United kingdom

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