TPA-induced arrest of erythroid differentiation is coupled with downregulation of GATA-1 and upregulation of GATA-2 in an erythroid cell line SAM-1.

Kamesaki, H; Michaud, G Y; Irving, S G; Suwabe, N; Kamesaki, S; Okuma, M; Cossman, J

Kamesaki, H; Michaud, G Y; Irving, S G; Suwabe, N; Kamesaki, S; Okuma, M; Cossman, J.

Affiliation

Kamesaki H; Laboratory of Experimental Radiology, Aichi Cancer Center Research Institute, Nagoya, Japan.

Blood ; 87(3): 999-1005, 1996 Feb 01.

Article in En | MEDLINE | ID: mdl-8562972

Subject(s)

DNA-Binding Proteins/biosynthesis; Erythroid Precursor Cells/drug effects; Erythropoiesis/drug effects; Gene Expression Regulation/drug effects; Tetradecanoylphorbol Acetate/pharmacology; Transcription Factors/biosynthesis; Antigens, Differentiation/biosynthesis; Antigens, Differentiation/genetics; Biomarkers; Blast Crisis/pathology; Cell Differentiation/drug effects; DNA-Binding Proteins/genetics; DNA-Binding Proteins/physiology; Erythroid-Specific DNA-Binding Factors; GATA2 Transcription Factor; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/pathology; Megakaryocytes/cytology; Receptors, Estrogen/genetics; Recombinant Fusion Proteins/genetics; Recombinant Fusion Proteins/metabolism; Transcription Factors/genetics; Transcription Factors/physiology; Tumor Cells, Cultured

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Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Tetradecanoylphorbol Acetate / Erythroid Precursor Cells / Gene Expression Regulation / DNA-Binding Proteins / Erythropoiesis Language: En Journal: Blood Year: 1996 Document type: Article Affiliation country: Japan Country of publication: United States

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