The human purH gene product, 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. Cloning, sequencing, expression, purification, kinetic analysis, and domain mapping.

Rayl, E A; Moroson, B A; Beardsley, G P

Rayl, E A; Moroson, B A; Beardsley, G P.

Affiliation

Rayl EA; Department of Pediatrics, Yale University, New Haven, Connecticut 06510, USA.

J Biol Chem ; 271(4): 2225-33, 1996 Jan 26.

Article in En | MEDLINE | ID: mdl-8567683

Subject(s)

Acyltransferases/genetics; Hydroxymethyl and Formyl Transferases; Nucleotide Deaminases/genetics; Acyltransferases/metabolism; Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Cloning, Molecular; Consensus Sequence; DNA Primers/chemistry; DNA, Complementary/genetics; Formyltetrahydrofolates/metabolism; Gene Expression; Humans; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Nucleotide Deaminases/metabolism; Phosphoribosylaminoimidazolecarboxamide Formyltransferase; RNA, Messenger/genetics; Sequence Alignment; Sequence Homology, Amino Acid; Structure-Activity Relationship

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Collection: 01-internacional Database: MEDLINE Main subject: Acyltransferases / Hydroxymethyl and Formyl Transferases / Nucleotide Deaminases Limits: Animals / Humans Language: En Journal: J Biol Chem Year: 1996 Document type: Article Affiliation country: United States Country of publication: United States

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