A novel hematopoietic multilineage clone, Myl-D-7, is stromal cell-dependent and supported by an alternative mechanism(s) independent of stem cell factor/c-kit interaction.

Itoh, K; Friel, J; Kluge, N; Kina, T; Kondo-Takaori, A; Kawamata, S; Uchiyama, T; Ostertag, W

Itoh, K; Friel, J; Kluge, N; Kina, T; Kondo-Takaori, A; Kawamata, S; Uchiyama, T; Ostertag, W.

Affiliation

Itoh K; Heinrich-Pette-Institute for Experimental Virology and Immunology, Hamburg University, Germany.

Blood ; 87(8): 3218-28, 1996 Apr 15.

Article in En | MEDLINE | ID: mdl-8605337

Subject(s)

Biological Factors/physiology; Bone Marrow Cells; Connective Tissue/physiology; Hematopoietic Stem Cells/cytology; Animals; Apoptosis; Biomarkers/analysis; Cell Differentiation/drug effects; Cell Line; Cell Lineage; Clone Cells/cytology; Coculture Techniques; Colony-Forming Units Assay; Connective Tissue Cells; Culture Media, Conditioned; Defective Viruses/genetics; Female; Friend murine leukemia virus/genetics; Genetic Vectors/genetics; Helper Viruses/genetics; Hematopoietic Cell Growth Factors/analysis; Hematopoietic Cell Growth Factors/genetics; Hematopoietic Cell Growth Factors/pharmacology; Mice; Mice, Inbred DBA; Mice, Mutant Strains; Mice, SCID; Proto-Oncogene Proteins/biosynthesis; Proto-Oncogene Proteins/genetics; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-kit/physiology; Receptors, Growth Factor/analysis; Receptors, Growth Factor/genetics; Recombinant Proteins/pharmacology; Sarcoma Viruses, Murine/genetics; Spleen/cytology; Spleen Focus-Forming Viruses/genetics; Stem Cell Factor/physiology

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Collection: 01-internacional Database: MEDLINE Main subject: Bone Marrow Cells / Hematopoietic Stem Cells / Biological Factors / Connective Tissue Language: En Journal: Blood Year: 1996 Document type: Article Affiliation country: Germany Country of publication: United States

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