Mutations in katG gene sequences in isoniazid-resistant clinical isolates of Mycobacterium tuberculosis are rare.

Pretorius, G S; van Helden, P D; Sirgel, F; Eisenach, K D; Victor, T C

Pretorius, G S; van Helden, P D; Sirgel, F; Eisenach, K D; Victor, T C.

Affiliation

Pretorius GS; US/MRC Centre for Molecular and Cellular Biology, Department of Medical Physiology and Biochemistry, Medical School, University of Stellenbosch, Tygerberg, South Africa.

Antimicrob Agents Chemother ; 39(10): 2276-81, 1995 Oct.

Article in En | MEDLINE | ID: mdl-8619582

Subject(s)

Antitubercular Agents/pharmacology; Bacterial Proteins; Genes, Bacterial; Isoniazid/pharmacology; Mycobacterium tuberculosis/genetics; Peroxidases/genetics; Point Mutation; Base Sequence; Drug Resistance, Microbial; Humans; Molecular Sequence Data; Mycobacterium tuberculosis/drug effects; Polymerase Chain Reaction

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peroxidases / Bacterial Proteins / Point Mutation / Genes, Bacterial / Isoniazid / Mycobacterium tuberculosis / Antitubercular Agents Limits: Humans Language: En Journal: Antimicrob Agents Chemother Year: 1995 Document type: Article Affiliation country: South Africa Country of publication: United States

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