DNA-dependent protein kinase inhibitor (OK-1035) suppresses p21 expression in HCT116 cells containing wild-type p53 induced by adriamycin.

Take, Y; Kumano, M; Teraoka, H; Nishimura, S; Okuyama, A

Take, Y; Kumano, M; Teraoka, H; Nishimura, S; Okuyama, A.

Affiliation

Take Y; Banyu Research Institute, Tsukuba, Japan.

Biochem Biophys Res Commun ; 221(2): 207-12, 1996 Apr 16.

Article in En | MEDLINE | ID: mdl-8619835

Subject(s)

DNA-Binding Proteins; Doxorubicin/pharmacology; Gene Expression Regulation/drug effects; Hydrazones/pharmacology; Oncogene Protein p21(ras)/genetics; Protein Serine-Threonine Kinases/antagonists & inhibitors; Pyridones/pharmacology; Tumor Suppressor Protein p53/genetics; Amino Acid Sequence; Base Sequence; Consensus Sequence; DNA/drug effects; DNA Damage; DNA-Activated Protein Kinase; Humans; Molecular Sequence Data; Nuclear Proteins; Promoter Regions, Genetic; Tumor Cells, Cultured

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Collection: 01-internacional Database: MEDLINE Main subject: Pyridones / Doxorubicin / Oncogene Protein p21(ras) / Gene Expression Regulation / Tumor Suppressor Protein p53 / Protein Serine-Threonine Kinases / DNA-Binding Proteins / Hydrazones Limits: Humans Language: En Journal: Biochem Biophys Res Commun Year: 1996 Document type: Article Affiliation country: Japan Country of publication: United States

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