[Modifications of fractional uptake method for 123I-IMP].
Kaku Igaku
; 33(3): 285-91, 1996 Mar.
Article
in Ja
| MEDLINE
| ID: mdl-8622262
ABSTRACT
We intended to improve the fractional uptake (FU) method which was developed to quantify cerebral blood flow using 123I-IMP without blood sampling. The quantification of cardiac output (CO) using first-pass data was adapted to FU method while the original FU method used CO which was estimated from the body surface area of patients. Time-radioactivity curves of the lungs and brain were separately obtained by a small-field-of-view gamma camera. In 24 cases, mean cerebral blood flow (mCBF) obtained by the modified FU method showed the better correlation (r = 0.833, P< 0.001) to mCBF measured by the Patlak plot with 99mTc-HMPAO than the original FU method (r=0.667, p<0.01). With these modifications, the reliability of FU method could be improved and the modified FU method might be performed in the other institutions.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Cerebrovascular Circulation
/
Amphetamines
/
Iodine Radioisotopes
Limits:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Language:
Ja
Journal:
Kaku Igaku
Year:
1996
Document type:
Article
Affiliation country:
Japan