Expression of inositol 1,4,5-trisphosphate receptors in rat adrenocortical zones.
J Steroid Biochem Mol Biol
; 57(1-2): 13-7, 1996 Jan.
Article
in En
| MEDLINE
| ID: mdl-8645612
ABSTRACT
Previously we demonstrated the presence of InsP3R-I, -II and -III subtypes in the zona glomerulosa. Now we have examined the expression of different subtypes of inositol 1,4,5-trisphosphate receptor (InsP3R) in the inner zones of rat adrenal cortex. RNA extracted from decapsulated adrenal tissue (zonae fasciculata-reticularis and the medulla) or from fasciculata-reticularis cells was reverse transcribed. Subsequent polymerase chain reaction revealed the presence of InsP3R-I, -II and -III subtypes in decapsulated tissue but failed to demonstrate the expression of any known subtypes of InsP3R in fasciculata-reticularis cells. Accordingly, InsP3 receptors expressed in the decapsulated tissue are of medullary origin.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Calcium Channels
/
Zona Fasciculata
/
Zona Reticularis
/
Receptors, Cytoplasmic and Nuclear
Limits:
Animals
Language:
En
Journal:
J Steroid Biochem Mol Biol
Journal subject:
BIOLOGIA MOLECULAR
/
BIOQUIMICA
Year:
1996
Document type:
Article
Affiliation country:
Hungary