Target cell-induced apoptosis of interleukin-2-activated human natural killer cells: roles of cell surface molecules and intracellular events.

Yamauchi, A; Taga, K; Mostowski, H S; Bloom, E T

Yamauchi, A; Taga, K; Mostowski, H S; Bloom, E T.

Affiliation

Yamauchi A; Division of Cellular and Gene Therapies, Center for Biologics Evaluation Research, Food and Drug Administration.

Blood ; 87(12): 5127-35, 1996 Jun 15.

Article in En | MEDLINE | ID: mdl-8652825

Subject(s)

Apoptosis; CD18 Antigens/physiology; Cytotoxicity, Immunologic; Interleukin-2/pharmacology; Killer Cells, Lymphokine-Activated/cytology; Killer Cells, Natural/drug effects; Antibodies, Monoclonal/immunology; Antibodies, Monoclonal/pharmacology; Antigens, CD/immunology; Antigens, CD/physiology; Apoptosis/drug effects; Benzoquinones; CD18 Antigens/immunology; Cell Membrane/ultrastructure; Cysteine Endopeptidases/metabolism; DNA/analysis; Fas Ligand Protein; Humans; Killer Cells, Natural/immunology; Lactams, Macrocyclic; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/pathology; Lymphoma, Non-Hodgkin/pathology; Melanoma/pathology; Membrane Glycoproteins/genetics; Membrane Glycoproteins/physiology; Protease Inhibitors/pharmacology; Quinones/pharmacology; Recombinant Fusion Proteins/metabolism; Rifabutin/analogs & derivatives; Serine Endopeptidases/metabolism; Transfection; Tumor Cells, Cultured; fas Receptor/physiology

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Collection: 01-internacional Database: MEDLINE Main subject: Killer Cells, Natural / Killer Cells, Lymphokine-Activated / Interleukin-2 / Apoptosis / CD18 Antigens / Cytotoxicity, Immunologic Limits: Humans Language: En Journal: Blood Year: 1996 Document type: Article Country of publication: United States

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