Toxicity of ochratoxin A, its opened lactone form and several of its analogs: structure-activity relationships.

Xiao, H; Madhyastha, S; Marquardt, R R; Li, S; Vodela, J K; Frohlich, A A; Kemppainen, B W

Xiao, H; Madhyastha, S; Marquardt, R R; Li, S; Vodela, J K; Frohlich, A A; Kemppainen, B W.

Affiliation

Xiao H; Department of Animal Science, University of Manitoba, Winnipeg, Canada.

Toxicol Appl Pharmacol ; 137(2): 182-92, 1996 Apr.

Article in En | MEDLINE | ID: mdl-8661343

Subject(s)

Lactones/toxicity; Ochratoxins/toxicity; Animals; Bacillus/drug effects; Female; HeLa Cells; Humans; Hydrolysis; Iron Chelating Agents/metabolism; Iron Chelating Agents/pharmacology; Lactones/metabolism; Lactones/pharmacokinetics; Male; Microbial Sensitivity Tests; Ochratoxins/chemistry; Ochratoxins/pharmacokinetics; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship

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Collection: 01-internacional Database: MEDLINE Main subject: Lactones / Ochratoxins Limits: Animals / Female / Humans / Male Language: En Journal: Toxicol Appl Pharmacol Year: 1996 Document type: Article Affiliation country: Canada Country of publication: United States

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