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[Results of postoperative cervical node irradiation in carcinoma of the pharyngo-larynx. A study of the cooperative group of radiotherapists]. / Résultats de l'irradiation ganglionnaire cervicale postopératoire dans les carcinomes du pharyngolarynx. Etude du groupe coopérateur des radiothérapeutes de centre.
Hoffstetter, S; Malissard, L; N'Guyen, T D; Panis, X; Jung, G M; Bachaud, J M; Prevost, B; Quint, R; Chaplain, G; Eschwège, F; Rambert, P; Fleury-Touzeau, F.
Affiliation
  • Hoffstetter S; Centre Alexis-Vautrin, Vandoeuvre-lès-Nancy, France.
Bull Cancer Radiother ; 83(2): 86-9, 1996.
Article in Fr | MEDLINE | ID: mdl-8688224
From 1981 to 1985, 428 patients presenting with an epidermoid carcinoma of the hypopharynx and/or larynx were treated with a curative intent by surgical resection and postoperative irradiation. Two-thirds of the tumours were T3 and 60% of patients presented with a clinical node involvement. The rates of local failure were 8%, 18% and 13%, respectively, for cancers of the larynx, of the piriform sinus and of the posterior wall; the rates of regional failure were 8%, 23% and 13%, respectively. There is no head and neck site with either a high or low risk of recurrence after resection, but the capsular rupture remains a factor of poor prognosis. The survival rate at 5 years of the whole series is 38%, for laryngeal localisation it reaches 62%. The risk of metastases is related to the node involvement and the interval between surgery and irradiation.
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Collection: 01-internacional Database: MEDLINE Main subject: Carcinoma, Squamous Cell / Lymphatic Irradiation / Pharyngeal Neoplasms / Laryngeal Neoplasms Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: Fr Journal: Bull Cancer Radiother Journal subject: NEOPLASIAS Year: 1996 Document type: Article Affiliation country: France Country of publication: France
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Collection: 01-internacional Database: MEDLINE Main subject: Carcinoma, Squamous Cell / Lymphatic Irradiation / Pharyngeal Neoplasms / Laryngeal Neoplasms Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: Fr Journal: Bull Cancer Radiother Journal subject: NEOPLASIAS Year: 1996 Document type: Article Affiliation country: France Country of publication: France