Sequence analysis of a parvovirus B19 isolate and baculovirus expression of the non-structural protein.
Arch Virol
; 141(7): 1319-27, 1996.
Article
in En
| MEDLINE
| ID: mdl-8774690
ABSTRACT
Serology for parvovirus B19 has been hampered by limited availability of antigen which has often had to be isolated from viraemic blood donations. We have determined the sequence of the genome of one such isolate (Stu). It is 99% similar to the sequences of two other isolates (Wi and Au) except at the far 5'-end, where it is more similar to the terminus of another isolate (Ala/Alb). Recombinant nonstructural protein, NS, was constructed. Antibodies to NS, as well as to the capsid proteins, VP1/2, were detected in patients with B19 infection.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Parvovirus B19, Human
/
Genome, Viral
/
Viral Nonstructural Proteins
/
Capsid Proteins
Limits:
Animals
Language:
En
Journal:
Arch Virol
Year:
1996
Document type:
Article
Affiliation country:
United kingdom