Expression and characterization of human pancreatic preprocarboxypeptidase A1 and preprocarboxypeptidase A2.

Laethem, R M; Blumenkopf, T A; Cory, M; Elwell, L; Moxham, C P; Ray, P H; Walton, L M; Smith, G K

Laethem, R M; Blumenkopf, T A; Cory, M; Elwell, L; Moxham, C P; Ray, P H; Walton, L M; Smith, G K.

Affiliation

Laethem RM; Division of Cell Biology, Wellcome Research Laboratories, Research Triangle Park, North Carolina 27709, USA.

Arch Biochem Biophys ; 332(1): 8-18, 1996 Aug 01.

Article in En | MEDLINE | ID: mdl-8806703

Subject(s)

Carboxypeptidases/genetics; Enzyme Precursors/genetics; Pancreas/enzymology; Amino Acid Sequence; Animals; Base Sequence; Carboxypeptidases/chemistry; Carboxypeptidases/metabolism; Cattle; Cloning, Molecular; DNA Primers/genetics; Enzyme Precursors/chemistry; Enzyme Precursors/metabolism; Enzyme Stability; Gene Expression; Humans; Kinetics; Methotrexate/analogs & derivatives; Methotrexate/metabolism; Methotrexate/therapeutic use; Molecular Sequence Data; Neoplasms/drug therapy; Phenylalanine/analogs & derivatives; Phenylalanine/metabolism; Phenylalanine/therapeutic use; Prodrugs/metabolism; Prodrugs/therapeutic use; Rats; Saccharomyces cerevisiae/genetics; Sequence Homology, Amino Acid; Substrate Specificity; Temperature

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Collection: 01-internacional Database: MEDLINE Main subject: Pancreas / Carboxypeptidases / Enzyme Precursors Limits: Animals / Humans Language: En Journal: Arch Biochem Biophys Year: 1996 Document type: Article Affiliation country: United States Country of publication: United States

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