The human cut homeodomain protein can repress gene expression by two distinct mechanisms: active repression and competition for binding site occupancy.

Mailly, F; Bérubé, G; Harada, R; Mao, P L; Phillips, S; Nepveu, A

Mailly, F; Bérubé, G; Harada, R; Mao, P L; Phillips, S; Nepveu, A.

Affiliation

Mailly F; Department of Medicine, McGill University, Royal Victoria Hospital, Montreal, Quebec, Canada.

Mol Cell Biol ; 16(10): 5346-57, 1996 Oct.

Article in En | MEDLINE | ID: mdl-8816446

Subject(s)

Gene Expression Regulation; Homeodomain Proteins/metabolism; Nuclear Proteins/metabolism; Repressor Proteins/metabolism; Transcription, Genetic; Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Conserved Sequence; Drosophila melanogaster; Genes, Reporter; Homeodomain Proteins/biosynthesis; Humans; Mammals; Mice; Molecular Sequence Data; Nuclear Proteins/biosynthesis; Nuclear Proteins/chemistry; Recombinant Fusion Proteins/biosynthesis; Repetitive Sequences, Nucleic Acid; Repressor Proteins/biosynthesis; Repressor Proteins/chemistry; Sequence Homology, Amino Acid; Transcription Factors

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Repressor Proteins / Transcription, Genetic / Nuclear Proteins / Gene Expression Regulation / Homeodomain Proteins Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Mol Cell Biol Year: 1996 Document type: Article Affiliation country: Canada

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