Pharmacology of methylglyoxal: formation, modification of proteins and nucleic acids, and enzymatic detoxification--a role in pathogenesis and antiproliferative chemotherapy.

Thornalley, P J

Thornalley, P J.

Affiliation

Thornalley PJ; Department of Biological and Chemical Sciences, University of Essex, Colchester, UK.

Gen Pharmacol ; 27(4): 565-73, 1996 Jun.

Article in En | MEDLINE | ID: mdl-8853285

Subject(s)

Antineoplastic Agents/pharmacology; Nucleic Acids/drug effects; Proteins/drug effects; Pyruvaldehyde/pharmacology; Animals; Biotransformation; Humans; Neoplasms/drug therapy; Neoplasms/pathology; Pyruvaldehyde/metabolism; Pyruvaldehyde/therapeutic use; Pyruvaldehyde/toxicity

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Collection: 01-internacional Database: MEDLINE Main subject: Pyruvaldehyde / Nucleic Acids / Proteins / Antineoplastic Agents Type of study: Etiology_studies Limits: Animals / Humans Language: En Journal: Gen Pharmacol Year: 1996 Document type: Article Affiliation country: United kingdom Country of publication: United kingdom

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