Predicting injection site muscle damage. I: Evaluation of immediate release parenteral formulations in animal models.

Sutton, S C; Evans, L A; Rinaldi, M T; Norton, K A

Sutton, S C; Evans, L A; Rinaldi, M T; Norton, K A.

Affiliation

Sutton SC; Pharmaceutical R & D Department, Pfizer, Incorporated, Groton, Connecticut 06340, USA.

Pharm Res ; 13(10): 1507-13, 1996 Oct.

Article in En | MEDLINE | ID: mdl-8899842

Subject(s)

Drug Evaluation, Preclinical/methods; Injections, Intramuscular/adverse effects; Muscles/injuries; Acetylglucosaminidase/analysis; Animals; Chemistry, Pharmaceutical; Creatine Kinase/analysis; Digoxin/administration & dosage; Disease Models, Animal; Edema/drug therapy; Evaluation Studies as Topic; Hemorrhage/chemically induced; Male; Muscles/enzymology; Peroxidase/analysis; Rabbits; Rats; Rats, Sprague-Dawley

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Collection: 01-internacional Database: MEDLINE Main subject: Drug Evaluation, Preclinical / Injections, Intramuscular / Muscles Type of study: Diagnostic_studies / Evaluation_studies / Prognostic_studies / Risk_factors_studies Limits: Animals Language: En Journal: Pharm Res Year: 1996 Document type: Article Affiliation country: United States Country of publication: United States

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