Targeted disruption of the mouse topoisomerase I gene by camptothecin selection.

Morham, S G; Kluckman, K D; Voulomanos, N; Smithies, O

Morham, S G; Kluckman, K D; Voulomanos, N; Smithies, O.

Affiliation

Morham SG; Department of Pathology, University of North Carolina at Chapel Hill, 27599-7525, USA.

Mol Cell Biol ; 16(12): 6804-9, 1996 Dec.

Article in En | MEDLINE | ID: mdl-8943335

Subject(s)

Camptothecin/administration & dosage; DNA Topoisomerases, Type I/genetics; Enzyme Inhibitors/administration & dosage; Gene Expression Regulation, Developmental; Alleles; Animals; Female; Gene Expression Regulation, Developmental/drug effects; Gene Targeting; Mice; Pregnancy; Topoisomerase I Inhibitors; Transfection

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Camptothecin / DNA Topoisomerases, Type I / Gene Expression Regulation, Developmental / Enzyme Inhibitors Limits: Animals / Pregnancy Language: En Journal: Mol Cell Biol Year: 1996 Document type: Article Affiliation country: United States Country of publication: United States

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