Neuroinvasion by simian immunodeficiency virus coincides with increased numbers of perivascular macrophages/microglia and intrathecal immune activation.

Lane, J H; Sasseville, V G; Smith, M O; Vogel, P; Pauley, D R; Heyes, M P; Lackner, A A

Lane, J H; Sasseville, V G; Smith, M O; Vogel, P; Pauley, D R; Heyes, M P; Lackner, A A.

Affiliation

Lane JH; New England Regional Primate Research Center, Harvard Medical School, Southborough, Massachusetts 01772, USA.

J Neurovirol ; 2(6): 423-32, 1996 Dec.

Article in En | MEDLINE | ID: mdl-8972425

Subject(s)

Central Nervous System Diseases/virology; Macrophages/virology; Microglia/virology; Simian Acquired Immunodeficiency Syndrome/immunology; Simian Immunodeficiency Virus/isolation & purification; Animals; Brain/blood supply; Brain/pathology; Capillaries/chemistry; Central Nervous System Diseases/immunology; Cerebrovascular Circulation; DNA, Viral/analysis; Image Processing, Computer-Assisted; Immunohistochemistry; In Situ Hybridization; Leukocyte Count; Lymphocyte Activation/immunology; Macaca mulatta; Macrophages/chemistry; Macrophages/cytology; Male; Microglia/chemistry; Microglia/cytology; Quinolinic Acid/analysis; Simian Immunodeficiency Virus/genetics; Vascular Cell Adhesion Molecule-1/analysis

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Collection: 01-internacional Database: MEDLINE Main subject: Central Nervous System Diseases / Simian Acquired Immunodeficiency Syndrome / Simian Immunodeficiency Virus / Microglia / Macrophages Limits: Animals Language: En Journal: J Neurovirol Journal subject: NEUROLOGIA / VIROLOGIA Year: 1996 Document type: Article Affiliation country: United States

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