[Chorioretinal lymphoproliferative disorder induced by Epstein-Barr virus in lung transplantation]. / Désordre lymphoprolifératif chorioretinien induit par le virus Epstein-Barr chez un greffe pulmonaire.
Bull Soc Belge Ophtalmol
; 259: 109-13, 1995.
Article
in Fr
| MEDLINE
| ID: mdl-8983528
ABSTRACT
The Epstein-Barr virus (EBV) is the causative factor of the posttransplant lymphoproliferative syndromes. Some ocular cases were described. We report the case of a lung-transplanted 59 year old man who presented a chorioretinal lymphoproliferative syndrome. A B-cell monoclonality and numerous EBV genome copies were demonstrated in vitreous material by PCR. We suspect an intermediate stage between polyclonal lymphoproliferative syndrome and malignant lymphoma. A treatment with nucleoside analogs and immunosuppression decrease was successful. The positive clinical evolution was associated with a reduction of the EBV genome quantity.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Chorioretinitis
/
Lung Transplantation
/
Herpesvirus 4, Human
/
Immunosuppressive Agents
/
Lymphoproliferative Disorders
Limits:
Humans
/
Male
/
Middle aged
Language:
Fr
Journal:
Bull Soc Belge Ophtalmol
Year:
1995
Document type:
Article