The commonly deleted region at 9p21-22 in lymphoblastic leukemias spans at least 400 kb and includes p16 but not p15 or the IFN gene cluster.

Aguiar, R C; Sill, H; Goldman, J M; Cross, N C

Aguiar, R C; Sill, H; Goldman, J M; Cross, N C.

Affiliation

Aguiar RC; LRF Centre for Adult Leukaemia, Department of Haematology, Royal Postgraduate Medical School, Hammersmith Hospital, London, UK.

Leukemia ; 11(2): 233-8, 1997 Feb.

Article in En | MEDLINE | ID: mdl-9009086

Subject(s)

Carrier Proteins/genetics; Cell Cycle Proteins; Chromosomes, Human, Pair 9/genetics; Genes, Tumor Suppressor; Leukemia, Myeloid/genetics; Precursor Cell Lymphoblastic Leukemia-Lymphoma/genetics; Sequence Deletion; Tumor Suppressor Proteins; Acute Disease; Chromosomes, Human, Pair 9/ultrastructure; Chronic Disease; Cyclin-Dependent Kinase Inhibitor p15; Cyclin-Dependent Kinase Inhibitor p16; DNA, Neoplasm/genetics; Heterozygote; Humans; Interferon-alpha/genetics; Polymerase Chain Reaction; Tumor Cells, Cultured

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Collection: 01-internacional Database: MEDLINE Main subject: Chromosomes, Human, Pair 9 / Carrier Proteins / Leukemia, Myeloid / Genes, Tumor Suppressor / Sequence Deletion / Cell Cycle Proteins / Tumor Suppressor Proteins / Precursor Cell Lymphoblastic Leukemia-Lymphoma Type of study: Prognostic_studies Limits: Humans Language: En Journal: Leukemia Journal subject: HEMATOLOGIA / NEOPLASIAS Year: 1997 Document type: Article Affiliation country: United kingdom

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