Synthetic peptides derived from human MHC class I sequences delay allograft rejection in rodents and inhibit cell-mediated cytotoxicity in vivo and in vitro.

Cuturi, M C; Josien, R; Douillard, P; Giral, M; Soulillou, J P

Cuturi, M C; Josien, R; Douillard, P; Giral, M; Soulillou, J P.

Affiliation

Cuturi MC; Institut de Transplantation et de Recherche en Transplantation (ITERT), INSERM Unit, Nantes, France.

Immunol Rev ; 154: 5-20, 1996 Dec.

Article in En | MEDLINE | ID: mdl-9034861

Subject(s)

Cytotoxicity, Immunologic/drug effects; Graft Rejection/prevention & control; Histocompatibility Antigens Class I/pharmacology; Immunosuppressive Agents/pharmacology; Peptides/pharmacology; Animals; Graft Rejection/immunology; HLA-B Antigens/chemistry; HLA-B Antigens/pharmacology; Histocompatibility Antigens Class I/chemistry; Humans; Immunity, Cellular; Immunosuppressive Agents/chemical synthesis; Killer Cells, Natural/drug effects; Killer Cells, Natural/immunology; Peptides/chemical synthesis; Rodentia; Transplantation, Homologous/immunology

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Collection: 01-internacional Database: MEDLINE Main subject: Peptides / Histocompatibility Antigens Class I / Cytotoxicity, Immunologic / Graft Rejection / Immunosuppressive Agents Limits: Animals / Humans Language: En Journal: Immunol Rev Year: 1996 Document type: Article Affiliation country: France Country of publication: United kingdom

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