Disposition of the new antidiabetic agent pioglitazone in rats, dogs, and monkeys.

Maeshiba, Y; Kiyota, Y; Yamashita, K; Yoshimura, Y; Motohashi, M; Tanayama, S

Maeshiba, Y; Kiyota, Y; Yamashita, K; Yoshimura, Y; Motohashi, M; Tanayama, S.

Affiliation

Maeshiba Y; Drug Analysis and Pharmacokinetics Research Laboratories, Takeda Chemical Industries, Ltd., Osaka, Japan.

Arzneimittelforschung ; 47(1): 29-35, 1997 Jan.

Article in En | MEDLINE | ID: mdl-9037440

Subject(s)

Hypoglycemic Agents/pharmacokinetics; Thiazoles/pharmacokinetics; Thiazolidinediones; Administration, Oral; Animals; Area Under Curve; Biotransformation; Dogs; Half-Life; Hypoglycemic Agents/administration & dosage; In Vitro Techniques; Injections, Intravenous; Intestinal Absorption; Macaca fascicularis; Male; Pioglitazone; Rats; Rats, Sprague-Dawley; Thiazoles/administration & dosage; Tissue Distribution

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Collection: 01-internacional Database: MEDLINE Main subject: Thiazoles / Thiazolidinediones / Hypoglycemic Agents Type of study: Prognostic_studies Limits: Animals Language: En Journal: Arzneimittelforschung Year: 1997 Document type: Article Affiliation country: Japan

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