Synergistic antiproliferative activity of tamoxifen and docetaxel on three oestrogen receptor-negative cancer cell lines is mediated by the induction of apoptosis.

Ferlini, C; Scambia, G; Distefano, M; Filippini, P; Isola, G; Riva, A; Bombardelli, E; Fattorossi, A; Benedetti Panici, P; Mancuso, S

Ferlini, C; Scambia, G; Distefano, M; Filippini, P; Isola, G; Riva, A; Bombardelli, E; Fattorossi, A; Benedetti Panici, P; Mancuso, S.

Affiliation

Ferlini C; Department of Obstetrics and Gynecology, Catholic University of Sacred Heart, Rome, Italy.

Br J Cancer ; 75(6): 884-91, 1997.

Article in En | MEDLINE | ID: mdl-9062411

Subject(s)

Antineoplastic Combined Chemotherapy Protocols/pharmacology; Apoptosis/drug effects; G2 Phase/drug effects; Taxoids; Apoptosis/genetics; DNA Fragmentation; DNA, Neoplasm/analysis; DNA, Neoplasm/drug effects; Docetaxel; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Humans; Paclitaxel/administration & dosage; Paclitaxel/analogs & derivatives; Paclitaxel/pharmacology; Receptors, Estrogen; Tamoxifen/administration & dosage; Tamoxifen/pharmacology; Tumor Cells, Cultured/chemistry; Tumor Cells, Cultured/drug effects

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antineoplastic Combined Chemotherapy Protocols / G2 Phase / Apoptosis / Taxoids Limits: Humans Language: En Journal: Br J Cancer Year: 1997 Document type: Article Affiliation country: Italy Country of publication: United kingdom

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