Estrogenic activity of a dieldrin/toxaphene mixture in the mouse uterus, MCF-7 human breast cancer cells, and yeast-based estrogen receptor assays: no apparent synergism.

Ramamoorthy, K; Wang, F; Chen, I C; Norris, J D; McDonnell, D P; Leonard, L S; Gaido, K W; Bocchinfuso, W P; Korach, K S; Safe, S

Ramamoorthy, K; Wang, F; Chen, I C; Norris, J D; McDonnell, D P; Leonard, L S; Gaido, K W; Bocchinfuso, W P; Korach, K S; Safe, S.

Affiliation

Ramamoorthy K; Veterinary Physiology and Pharmacology, Texas A&M University, College Station 77843-4466, USA.

Endocrinology ; 138(4): 1520-7, 1997 Apr.

Article in En | MEDLINE | ID: mdl-9075711

Subject(s)

Dieldrin/pharmacology; Receptors, Estrogen/analysis; Toxaphene/pharmacology; Uterus/drug effects; Animals; Binding, Competitive; Breast Neoplasms/metabolism; Cell Division/drug effects; Dieldrin/administration & dosage; Drug Synergism; Estradiol/pharmacology; Female; Humans; Mice; Peroxidase/metabolism; Progesterone/metabolism; Rats; Toxaphene/administration & dosage; Transfection; Tumor Cells, Cultured; Uterus/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Toxaphene / Uterus / Receptors, Estrogen / Dieldrin Limits: Animals / Female / Humans Language: En Journal: Endocrinology Year: 1997 Document type: Article Affiliation country: United States Country of publication: United States

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