Structural and functional aspects of rat microsomal glutathione transferase. The roles of cysteine 49, arginine 107, lysine 67, histidine, and tyrosine residues.

Weinander, R; Ekström, L; Andersson, C; Raza, H; Bergman, T; Morgenstern, R

Weinander, R; Ekström, L; Andersson, C; Raza, H; Bergman, T; Morgenstern, R.

Affiliation

Weinander R; Institute of Environmental Medicine, Division of Biochemical Toxicology, Karolinska Institutet, Box 210, S-171 77 Stockholm, Sweden.

J Biol Chem ; 272(14): 8871-7, 1997 Apr 04.

Article in En | MEDLINE | ID: mdl-9083005

Subject(s)

Glutathione Transferase/metabolism; Microsomes, Liver/enzymology; Amino Acid Sequence; Animals; Arginine; Cysteine; Enzyme Inhibitors/pharmacology; Glutathione Transferase/chemistry; Histidine; Indicators and Reagents/pharmacology; Lysine; Male; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylglyoxal/pharmacology; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Trinitrobenzenesulfonic Acid/pharmacology; Tyrosine

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Collection: 01-internacional Database: MEDLINE Main subject: Microsomes, Liver / Glutathione Transferase Limits: Animals Language: En Journal: J Biol Chem Year: 1997 Document type: Article Affiliation country: Sweden

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