Functional intestinal hypomotility in association with neuronal damage in a dog.
J Small Anim Pract
; 38(3): 119-23, 1997 Mar.
Article
in En
| MEDLINE
| ID: mdl-9097244
ABSTRACT
A young, crossbred dog with a 13-month history of progressively worsening, recurrent episodes of vomiting, anorexia, depression and dehydration was diagnosed as having a functional hypomotility disorder of the small intestines. During hospitalisation, the dog's condition improved only when total parenteral nutrition was administered. When fed orally, the dog developed severe gastric dilatation. Intestinal motility was minimal, but was induced by neostigmine. Post mortem findings included dilatation of the duodenum and progressive narrowing of the small bowel up to the ileum. Histopathology revealed various grades of neuronal degeneration and necrosis of the myenteric plexuses throughout the small intestine. Microscopic changes resembled those reported in dysautonomia, but were limited to small intestinal myenteric plexuses. A localised congenital neuronal defect causing a lack of parasympathetic tone is suspected.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Dog Diseases
/
Gastrointestinal Motility
/
Intestinal Diseases
/
Myenteric Plexus
Type of study:
Diagnostic_studies
/
Risk_factors_studies
Limits:
Animals
Language:
En
Journal:
J Small Anim Pract
Year:
1997
Document type:
Article
Affiliation country:
Israel