Engagement of the signaling lymphocytic activation molecule (SLAM) on activated T cells results in IL-2-independent, cyclosporin A-sensitive T cell proliferation and IFN-gamma production.

Aversa, G; Chang, C C; Carballido, J M; Cocks, B G; de Vries, J E

Aversa, G; Chang, C C; Carballido, J M; Cocks, B G; de Vries, J E.

Affiliation

Aversa G; DNAX Research Institute of Molecular and Cellular Biology, Human Immunology Department, Palo Alto, CA 94304, USA.

J Immunol ; 158(9): 4036-44, 1997 May 01.

Article in En | MEDLINE | ID: mdl-9126961

Subject(s)

Glycoproteins/physiology; Immunoglobulins/physiology; Receptors, Immunologic/immunology; T-Lymphocytes/immunology; Antibodies, Monoclonal/immunology; Antigens, CD; CD4-Positive T-Lymphocytes/immunology; CD8-Positive T-Lymphocytes/immunology; Cyclosporine/pharmacology; Flow Cytometry; Gene Expression; Humans; Interferon-gamma/biosynthesis; Interleukin-2/physiology; Lymphocyte Activation; RNA, Messenger/genetics; Receptors, Cell Surface; Signaling Lymphocytic Activation Molecule Family Member 1; T-Lymphocytes/cytology; Th1 Cells/immunology; Up-Regulation

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Collection: 01-internacional Database: MEDLINE Main subject: Immunoglobulins / Glycoproteins / Receptors, Immunologic / T-Lymphocytes Type of study: Diagnostic_studies Limits: Humans Language: En Journal: J Immunol Year: 1997 Document type: Article Affiliation country: United States Country of publication: United States

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