Structural insights into the evolution of an antibody combining site.

Wedemayer, G J; Patten, P A; Wang, L H; Schultz, P G; Stevens, R C

Wedemayer, G J; Patten, P A; Wang, L H; Schultz, P G; Stevens, R C.

Affiliation

Wedemayer GJ; Department of Chemistry, University of California, Berkeley, CA 94720, USA.

Science ; 276(5319): 1665-9, 1997 Jun 13.

Article in En | MEDLINE | ID: mdl-9180069

Subject(s)

Antibodies, Catalytic/chemistry; Binding Sites, Antibody; Evolution, Molecular; Immunoglobulin Fab Fragments/chemistry; Antibodies, Catalytic/genetics; Antibodies, Catalytic/immunology; Antibody Affinity; Antibody Diversity; Antigen-Antibody Complex; Antigen-Antibody Reactions; Binding Sites; Crystallography, X-Ray; Haptens/immunology; Hydrogen Bonding; Immunoglobulin Fab Fragments/genetics; Immunoglobulin Fab Fragments/immunology; Molecular Sequence Data; Mutation; Protein Conformation; Protein Structure, Secondary

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Collection: 01-internacional Database: MEDLINE Main subject: Binding Sites, Antibody / Immunoglobulin Fab Fragments / Antibodies, Catalytic / Evolution, Molecular Language: En Journal: Science Year: 1997 Document type: Article Affiliation country: United States

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