Transformation of chicken cells by the gene encoding the catalytic subunit of PI 3-kinase.

Chang, H W; Aoki, M; Fruman, D; Auger, K R; Bellacosa, A; Tsichlis, P N; Cantley, L C; Roberts, T M; Vogt, P K

Chang, H W; Aoki, M; Fruman, D; Auger, K R; Bellacosa, A; Tsichlis, P N; Cantley, L C; Roberts, T M; Vogt, P K.

Affiliation

Chang HW; Department of Molecular and Experimental Medicine, Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

Science ; 276(5320): 1848-50, 1997 Jun 20.

Article in En | MEDLINE | ID: mdl-9188528

Subject(s)

Avian Sarcoma Viruses/genetics; Cell Transformation, Neoplastic; Cell Transformation, Viral; Oncogenes; Phosphotransferases (Alcohol Group Acceptor)/genetics; Amino Acid Sequence; Animals; Avian Sarcoma Viruses/physiology; Cells, Cultured; Chick Embryo; Chickens; Cloning, Molecular; Enzyme Activation; Genes, Viral; Hemangiosarcoma/genetics; Hemangiosarcoma/virology; Molecular Sequence Data; Phosphatidylinositol 3-Kinases; Phosphatidylinositol Phosphates/metabolism; Phosphotransferases (Alcohol Group Acceptor)/metabolism; Platelet-Derived Growth Factor/pharmacology; Protein Serine-Threonine Kinases/metabolism; Proto-Oncogene Proteins/metabolism; Proto-Oncogene Proteins c-akt; Signal Transduction; Transfection

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Collection: 01-internacional Database: MEDLINE Main subject: Oncogenes / Cell Transformation, Neoplastic / Cell Transformation, Viral / Phosphotransferases (Alcohol Group Acceptor) / Avian Sarcoma Viruses Limits: Animals Language: En Journal: Science Year: 1997 Document type: Article Affiliation country: United States Country of publication: United States

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