Osteoradionecrosis of the jaws: a retrospective study of the background factors and treatment in 104 cases.
J Oral Maxillofac Surg
; 55(6): 540-4; discussion 545-6, 1997 Jun.
Article
in En
| MEDLINE
| ID: mdl-9191633
ABSTRACT
PURPOSE:
This study analyzed potential risk factors in patients who received radiation therapy and then developed osteoradionecrosis (ORN). PATIENTS ANDMETHODS:
A group of 104 patients who developed osteoradionecrosis of the jaws were reviewed treated between 1972 and 1992.RESULTS:
The most common affected site was the mandible (99 cases, 95.2%), followed by the maxilla (5 cases, 4.8%). Among all cases, 93 (89.4%) were induced-trauma ORN, and 11 (10.6%) were spontaneous ORN. The following risk factors were considered as predisposing factors for the appearance of ORN Anatomic location of the tumor, tumor surgery, total radiation dose, dose rate/day, mode of radiation delivery, time from radiation therapy until the onset of ORN, and dental status. ORN developed more frequently with oral cancer than other head and neck cancers. The size of the tumor seemed not to influence the incidence of ORN except when the tumor invade the adjacent bone. Type of radiation delivery total bone dose, and modes of radiation appeared to influence the risk of ORN occurrence. After conservative treatment, 44 (42.3%) cases had complete healing and resolution 34 (32.6%) cases had a stable, chronic ORN process, and 26 (25.1%) cases had acute and progressive ORN.CONCLUSION:
An understanding of the risk factors is important in preventing ORN after radiation therapy.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Osteoradionecrosis
/
Jaw Diseases
/
Cranial Irradiation
/
Dental Care for Chronically Ill
Type of study:
Etiology_studies
/
Observational_studies
/
Risk_factors_studies
Limits:
Adolescent
/
Adult
/
Aged
/
Child
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
J Oral Maxillofac Surg
Year:
1997
Document type:
Article
Affiliation country:
Brazil