Chronic, topical administration of 4-aminobiphenyl induces tissue-specific DNA adducts in mice.

Underwood, P M; Zhou, Q; Jaeger, M; Reilman, R; Pinney, S; Warshawsky, D; Talaska, G

Underwood, P M; Zhou, Q; Jaeger, M; Reilman, R; Pinney, S; Warshawsky, D; Talaska, G.

Affiliation

Underwood PM; Department of Environmental Health, University of Cincinnati Medical Center, Ohio 45267-0056, USA.

Toxicol Appl Pharmacol ; 144(2): 325-31, 1997 Jun.

Article in En | MEDLINE | ID: mdl-9194416

Subject(s)

Aminobiphenyl Compounds/toxicity; Carcinogens/toxicity; DNA Adducts/drug effects; Administration, Cutaneous; Aminobiphenyl Compounds/administration & dosage; Animals; Carcinogens/administration & dosage; DNA/chemistry; DNA/isolation & purification; DNA Adducts/analysis; Female; Liver/drug effects; Liver/metabolism; Mice; Skin/drug effects; Skin/metabolism; Time Factors; Tissue Distribution/genetics; Urinary Bladder/drug effects; Urinary Bladder/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Carcinogens / DNA Adducts / Aminobiphenyl Compounds Limits: Animals Language: En Journal: Toxicol Appl Pharmacol Year: 1997 Document type: Article Affiliation country: United States Country of publication: United States

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