Human- and mouse-inducible nitric oxide synthase promoters require activation of phosphatidylcholine-specific phospholipase C and NF-kappa B.

Spitsin, S V; Farber, J L; Bertovich, M; Moehren, G; Koprowski, H; Michaels, F H

Spitsin, S V; Farber, J L; Bertovich, M; Moehren, G; Koprowski, H; Michaels, F H.

Affiliation

Spitsin SV; Biotechnology Foundation Laboratories, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.

Mol Med ; 3(5): 315-26, 1997 May.

Article in En | MEDLINE | ID: mdl-9205947

Subject(s)

NF-kappa B/metabolism; Nitric Oxide Synthase/genetics; Transcriptional Activation; Type C Phospholipases/metabolism; Animals; Antioxidants/pharmacology; Blotting, Western; Bridged-Ring Compounds/pharmacology; Cell Line; Cytokines/metabolism; Epithelium; Gene Expression; Humans; Lipid Metabolism; Lung/cytology; Lung/metabolism; Macrophages/cytology; Macrophages/metabolism; Mice; NF-kappa B/antagonists & inhibitors; Nitric Oxide/metabolism; Nitric Oxide Synthase/metabolism; Norbornanes; Phosphatidylcholines/metabolism; Phosphodiesterase Inhibitors/pharmacology; RNA, Messenger; RNA-Binding Proteins/metabolism; Ribonucleases; Thiocarbamates; Thiones/pharmacology; Type C Phospholipases/antagonists & inhibitors

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Type C Phospholipases / Transcriptional Activation / NF-kappa B / Nitric Oxide Synthase Limits: Animals / Humans Language: En Journal: Mol Med Journal subject: BIOLOGIA MOLECULAR Year: 1997 Document type: Article Affiliation country: United States Country of publication: United kingdom

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