Contribution of hydrophobicity of nonionic detergents to membrane lipid fluidity and disopyramide uptake by rat intestinal brush-border membrane vesicles.

Koga, K; Murakami, M; Kawashima, S

Koga, K; Murakami, M; Kawashima, S.

Affiliation

Koga K; Division of Pharmaceutical Information, Faculty of Pharmaceutical Sciences, Hokuriku University, Kanazawa, Japan.

Biol Pharm Bull ; 20(6): 674-9, 1997 Jun.

Article in En | MEDLINE | ID: mdl-9212989

Subject(s)

Detergents/pharmacology; Disopyramide/metabolism; Intestine, Small/drug effects; Membrane Fluidity/drug effects; Membrane Lipids/metabolism; Animals; Biological Transport/drug effects; Cell Membrane/drug effects; Cell Membrane/metabolism; Detergents/chemistry; Fluorescent Dyes; In Vitro Techniques; Intestine, Small/metabolism; Intestine, Small/ultrastructure; Male; Microvilli/drug effects; Microvilli/metabolism; Rats; Rats, Wistar; Spectrometry, Fluorescence; Structure-Activity Relationship

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Collection: 01-internacional Database: MEDLINE Main subject: Detergents / Disopyramide / Intestine, Small / Membrane Fluidity / Membrane Lipids Limits: Animals Language: En Journal: Biol Pharm Bull Journal subject: BIOQUIMICA / FARMACOLOGIA Year: 1997 Document type: Article Affiliation country: Japan Country of publication: Japan

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