Induction of c-fos gene expression by spinal cord transection in Sus scrofa.
Brain Res
; 759(2): 301-5, 1997 Jun 13.
Article
in En
| MEDLINE
| ID: mdl-9221952
ABSTRACT
Functional responses of primary sensory afferents and spinal cord were monitored in swine subjected to a high cervical (C1) spinal transection. Two and a half hours after transection, dorsal root ganglia and cervical and thoracolumbar spinal segments were processed immunocytochemically for the c-fos gene product, Fos and related antigens. In spinal-transected animals, Fos-like immunoreactivity (FLI) was induced in spinal laminae I, V, VII and X and the intermediolateral cell column but not in sensory ganglia as compared to controls spinal-intact age-matched littermates. Spinal laminae expressing FLI harbor sympathetic and somatic interneurons and may aid in maintaining sympathetic outflow.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Spinal Cord Injuries
/
Gene Expression
/
Proto-Oncogene Proteins c-fos
Limits:
Animals
Language:
En
Journal:
Brain Res
Year:
1997
Document type:
Article
Affiliation country:
United States
Publication country:
HOLANDA
/
HOLLAND
/
NETHERLANDS
/
NL
/
PAISES BAJOS
/
THE NETHERLANDS