Failure to find an association between hepatitis C virus and thyroid autoimmunity.
Thyroid
; 7(3): 421-4, 1997 Jun.
Article
in En
| MEDLINE
| ID: mdl-9226214
A high frequency of hepatitis C antibodies has been reported from France in patients with autoimmune thyroiditis. Two cases of Hashimoto's thyroiditis in association with chronic active hepatitis and hepatitis C infection have also been reported. We have examined this potential association in 46 patients with autoimmune hypothyroidism and found that 16 apparently had hepatitis C antibodies in one of the two commercially available enzyme-linked immunosorbent assays (ELISA), but all patients were negative in a confirmatory commercially available recombinant immunoblot assay (RIBA-3) indicating that none of the patients were truly positive for hepatitis C antibodies. We also tested sera from 111 patients with proven hepatitis C infection and found no increased prevalence of thyroid autoantibodies. These results suggest that hepatitis C infection is not a risk factor for the development of thyroid autoimmunity in the United Kingdom.
Search on Google
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Thyroiditis, Autoimmune
/
Hepatitis C
Type of study:
Risk_factors_studies
Limits:
Adult
/
Female
/
Humans
/
Male
Language:
En
Journal:
Thyroid
Journal subject:
ENDOCRINOLOGIA
Year:
1997
Document type:
Article
Affiliation country:
United kingdom
Country of publication:
United States