In vivo depletion of host CD4+ and CD8+ cells permits engraftment of bone marrow stem cells and tolerance induction with minimal conditioning.

Exner, B G; Colson, Y L; Li, H; Ildstad, S T

Exner, B G; Colson, Y L; Li, H; Ildstad, S T.

Affiliation

Exner BG; Institute for Cellular Therapeutics, Allegheny University of the Health Sciences, Philadelphia, Pa. 19102, USA.

Surgery ; 122(2): 221-7, 1997 Aug.

Article in En | MEDLINE | ID: mdl-9288126

Subject(s)

Bone Marrow Transplantation/immunology; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Hematopoietic Stem Cell Transplantation; Lymphocyte Depletion; Animals; Antibodies, Monoclonal; Antilymphocyte Serum/therapeutic use; Chimera; Cyclophosphamide/pharmacology; Immunosuppressive Agents/pharmacology; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Whole-Body Irradiation

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Collection: 01-internacional Database: MEDLINE Main subject: CD4-Positive T-Lymphocytes / Bone Marrow Transplantation / Lymphocyte Depletion / Hematopoietic Stem Cell Transplantation / CD8-Positive T-Lymphocytes Limits: Animals Language: En Journal: Surgery Year: 1997 Document type: Article Affiliation country: United States Country of publication: United States

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